Organisation profile
Organisation profile
The Centre focuses on multidisciplinary aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression to target national and global challenges to health.
The Research Centre aims to:
- Bring together researchers examining physiological, psychological and biomechanical aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression.
- Develop research capacity by providing training for undergraduate to postdoctoral researchers and supporting early career researchers to become independent research leaders targeting national and global challenges to health.
The Centre for Physical Activity and Life Sciences is a multidisciplinary Centre including expertise in Biosciences, Sport & Exercise Sciences, Podiatry, and Occupational Therapy. The Centre includes three main Special Interest Groups; Molecular Biosciences, Sport & Exercise Medicine, and Interdisciplinary Physical Activity & Health Promotion. The main interests of researchers in these Groups are outlined below:
- Molecular Biosciences
- Immunogenetics
- Clinical genetics and genomics
- RNA-based gene therapy
- Cancer biology
- Neuromuscular and neurodegenerative disorders
- Monozygotic twin studies
- Bioethics
- Antimicrobial resistance
- Molecular Mechanisms of Bacterial Pathogenesis
- Infection control
- Sport & Exercise Medicine
- Functional decline during ageing and fall risk
- Sarcopenia and osteoporosis
- Eccentric exercise in healthy and ageing populations
- Cognitive impairment, pain and balance in ageing
- Tendinopathy
- Muscle stretching techniques and strain injury
- Isometric resistance training and hypertension
- Exercise-induced muscle damage
- Heat- and cryo-based therapy
- Concussion in impact sports Infection control
- Interdisciplinary Physical Activity & Health Promotion
- Social exercise prescription in the built environment
- Dancing groups to promote older adult health
- Sociology of physical activity
- Whole-systems partnership development
- Child physical activity and nutrition programmes
Keywords
- RC1200 Sports Medicine
Fingerprint
Profiles
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Prof Anthony Baross
- University of Northampton, School of Sport and Public Health - Professor of Cardiovascular Physiology
- Centre for Physical Activity and Life Sciences
Person: Academic
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Dr Brett Baxter
- University of Northampton, School of Sport and Public Health - Senior Lecturer Sport Exercise Science (Biomechanics)
- Centre for Physical Activity and Life Sciences
Person: Academic
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Evaluation of Move Northamptonshire
Ryan, D. (PI) & Mason, J. (CoI)
10/04/24 → 10/04/29
Project: Research › Contract Research with non-commercial organisations
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Home based isometric resistance band training to reduce blood pressure in West Northamptonshire.
Baross, A. (PI), Jones, P. (CoI) & Wright, B. (CoI)
1/10/23 → 1/07/26
Project: Research › Local Government
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Understanding the value of sociology in raising engagement, attainment, and retention amongst level 4 sport students
Mason, J. (PI) & Hardwicke, J. (CoI)
Project: Internal Fund › Quality-related Research (QR) Fund
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“Peer-Assisted Learning (PAL) Initiative for Inclusive Student Success in Core Clinical Modules for Biomedical Science Students”
Farahani, M. (PI)
Project: Internal Fund › Student Success Innovation Fund
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Sport England Place Partnership Evaluator
Ryan, D. (PI) & Bayes, N. (CoI)
1/04/25 → 10/04/26
Project: Research › Charitable Funding
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Influence of Intended Slow and Fast Eccentric Back Squat Velocity on Subsequent Countermovement Jump Performance
Zarkadoula, A., Tsatalas, T., Kay, A. D., Blazevich, A. J., Kokkotis, C., Plakias, S., Baxter, B. A., Van Enis, A., Giakas, G. & Mina, M. A., 31 Mar 2026, In: Journal of Functional Morphology and Kinesiology. 11, 2, p. 1-16 16 p., 143.Research output: Contribution to Journal › Article › peer-review
Open AccessFile -
Molecular Dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties
Young, D., Arias-Gaguancela, O., Gibson, F., Grainger, M., Score, J., Nathubhai, A., Cafiero, M. & Machado, L., 1 May 2026, In: FEBS Open Bio. 18 p.Research output: Contribution to Journal › Article › peer-review
Open AccessFile -
Move Northamptonshire Evaluation and Learning Plan
Ryan, D., Mason, J. & Bayes, T., 9 Feb 2026, University of Northampton. 56 p.Research output: Book/Report › Technical Report
Open AccessFile -
The effects of simultaneous isometric and eccentric- or concentric-biased exercise on cardiovascular and muscular health of young individuals. Simultaneous handgrip and stair walking improves cardiovascular health
Baross, A., Wright, B., Langdon, D., Kay, T., Cauchi, M., Clarke, A., Pithan, B., Willimont, C., Barnett, T., Key, C., reynolds, M., Thomas, A. & Baxter, B. A., 2 Jan 2026, (Accepted/In press) In: European Journal of Applied Physiology.Research output: Contribution to Journal › Article › peer-review
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17β-oestradiol and melanoma: Uncovering the effects of oestrogen on cell proliferation, viability and oestrogen receptor expression
Oday Hussian, R. & Machado, L., 7 May 2025, (Accepted/In press) In: Journal of Bioscience and Applied Research. 11Research output: Contribution to Journal › Article › peer-review
Datasets
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The Underrepresentation of Women in Esports Leadership Positions: Exploring the Barriers and Facilitating Factors
Gray, S. (Creator) & Zhu, L. (Creator), University of Northampton, 17 Aug 2024
DOI: 10.24339/d23611b1-3118-45e2-9851-bbb3edfc449d
Dataset
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Dataset: Standing balance as a potential screening tool for detecting cognitive impairment
Krampah, J. O. (Creator), Kay, T. (Contributor), Anthony, K. (Contributor) & Campbell, J. (Contributor), University of Northampton, 26 Feb 2026
DOI: 10.24339/753549a3-2b65-4326-95da-6cfc1d3e798e
Dataset
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Dataset: Exploring the utility of salivary biomarkers as non-invasive markers of declining cognitive function in older adults
Krampah, J. O. (Creator), Campbell, J. (Contributor), Kay, T. (Contributor) & Anthony, K. (Contributor), University of Northampton, 26 Feb 2026
DOI: 10.24339/ce5fadef-f08c-4176-955b-abfe708cdfc7
Dataset
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Dataset: The reliability and suitability of different foot positions for standing balance assessment in older adults
Krampah, J. (Creator), Kay, T. (Contributor), Anthony, K. (Contributor) & Campbell, J. (Contributor), University of Northampton, 10 Apr 2025
DOI: 10.24339/399523b7-afa1-4882-93ad-1bb3287726c7
Dataset
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Supplementary Manual Count Data for Intercept Go-Along Interviews within Delapre Park, Hunsbury Hill, and Upton Country Park,
Ryan, D. (Creator), Hardwicke, J. (Contributor) & Hill, K. (Contributor), University of Northampton, 31 Dec 2024
DOI: 10.24339/4689cd3d-f36f-470a-aa70-ed38503a3871
Dataset
Activities
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Archaeological Resource Centre (ARC) at Chester House Estate in Irchester
Schaber, F. (Academic), Williams, A. N. (Academic) & Ben Donnelly-Symes, B. (Academic)
26 Apr 2026Activity: Public Engagement and Outreach › Heritage Events › Knowledge Exchange
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Midlands Innovation Flow Cytometry Meeting 2026
Machado, L. (Participant)
6 Mar 2026Activity: Organising a conference or workshop › Knowledge Exchange
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NASP Tutorial Capturing and Utilising Data for Green Social Prescribing Delapré Abbey
Ryan, D. (Invited speaker) & Clinton, R. (Invited speaker)
13 Mar 2026Activity: Academic Talks or Presentations › Invited talk › Knowledge Exchange
File -
Exploring green spaces, play and learning opportunities
Whewell, E. (Consultant), Ryan, D. (Consultant) & Tiplady, H. (Consultant)
27 Apr 2026Activity: Other Knowledge Exchange or Research Activity › Industry Engagement › Knowledge Exchange
File -
Cafe Scientifique: Let’s go to the park – why greenspaces are important for Northampton’s residents.
Ryan, D. (Invited speaker)
18 Sept 2025Activity: Academic Talks or Presentations › Seminar/Workshop › Knowledge Exchange
File
Impacts
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FDA approves first drug to treat Duchenne muscular dystrophy (DMD)
Anthony, K. (Co-Investigator)
Impact: Public policy impacts, Health and Well-Being impacts, Quality of life impacts, 03: Good Health and Well-Being (UN SDG)
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Identification of the microorganisms responsible for acute head and neck infections
Woodacre, A. (Principal Investigator), Cox, J. (Co-Investigator), Score, J. (Co-Investigator) & Ameerally, P. (Facilitator)
Impact: 03: Good Health and Well-Being (UN SDG)
Student theses
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Admission patterns of paediatric patients aged 0-4 years diagnosed with respiratory conditions between Emergency Department (ED) and acute paediatrics and its relationship to zero-day admissions.
Wright, V. (Author), Harris, N. (Supervisor) & Beeson, P. (Supervisor), Jul 2020Student thesis: Doctoral Thesis
File -
Characterising the Role of the Calcium-dependent Citrullinating Enzyme Peptidyl Arginine Deiminase 2 in Ovarian Cancer
Albalbeisi, N. (Author), Livingstone, I. (Supervisor), Machado, L. (Supervisor) & Anthony, K. (Supervisor), Oct 2019Student thesis: Doctoral Thesis
File -
Exploring domestic rabbit (Oryctolagus cuniculus) personality utilising behaviour coding, behaviour testing and a novel behaviour rating tool
Ellis, C. F. (Author), Holt, C. (Supervisor) & McCormick, W. (Supervisor), Sept 2020Student thesis: Doctoral Thesis
File -
Investigating a Role for the Duchenne Muscular Dystrophy Gene in the Tumourigenesis of Head and Neck Cancer
Jones, L. (Author), Machado, L. (Supervisor) & Anthony, K. (Supervisor), 27 Mar 2024Student thesis: Doctoral Thesis
File -
The acute and chronic effects of resistance exercise with and without blood flow restriction on fall risk factors in older adults
Langdon, D. (Author), Kay, T. (Director of Studies), Baross, A. (Supervisor) & Hill, M. (Supervisor), 25 Mar 2025Student thesis: Doctoral Thesis
File
Press/Media
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Member of Parliament visits University of Northampton to explore link between health and economic growth
28/10/25
1 item of Media coverage
Press/Media
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BBC News Child Hospital Care dates from the 18th century - study
Williams, A. N.
17/09/25
1 Media contribution
Press/Media
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NGH archives to rewrite the story of how hospital paediatric care began
Williams, A. N.
16/09/25
1 Media contribution
Press/Media
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4000 named children treated at Northampton Infirmary 1744-1801
Williams, A. N.
15/09/25
1 item of Media coverage
Press/Media
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University of Northampton researcher leads research for active travel improvements
12/08/25
1 item of Media coverage
Press/Media