Organization profile

Organisation profile

The Centre focuses on physiological, psychological and biomechanical aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression to target national and global challenges to health.

The Research Centre aims to:

  • Bring together researchers examining physiological, psychological and biomechanical aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression.
  • Develop research capacity by providing training for undergraduate to postdoctoral researchers and supporting early career researchers to become independent research leaders targeting national and global challenges to health.

The Centre for Physical Activity and Life Sciences is a multidisciplinary Centre including expertise in Biosciences, Sport & Exercise Sciences, Podiatry, and Occupational Therapy.  The Centre includes two main Research Groups (Molecular Biosciences Research Group, Neuromuscular and Musculoskeletal Research Group) with the main interests of researchers in these Groups outlined below:

  • Molecular Biosciences Research Group
    • Immunogenetics
    • Clinical genetics and genomics
    • RNA-based gene therapy
    • Cancer biology
    • Neuromuscular and neurodegenerative disorders
    • Monozygotic twin studies
    • Bioethics
    • Antimicrobial resistance
    • Molecular Mechanisms of Bacterial Pathogenesis
    • Infection control
  • Neuromuscular and Musculoskeletal Research Group
    • Functional decline during ageing and fall risk
    • Sarcopenia and osteoporosis
    • Eccentric exercise in healthy and ageing populations
    • Cognitive impairment, pain and balance in ageing
    • Muscle stretching techniques and strain injury
    • Isometric resistance training and hypertension
    • Exercise-induced muscle damage
    • Heat- and cryo-based therapy
    • Stroke rehabilitation
    • Concussion in impact sports

Fingerprint Dive into the research topics where Centre for Physical Activity and Life Sciences is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

  • Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects

    Research Design Service East Midlands Public Involvement Fund

    Kay, T.

    1/10/181/11/18

    Project: EnterpriseConsultancy Charity

    Research Output

    An Updated Classification System and Review of the Lipooligosaccharide Biosynthesis Gene Locus in Campylobacter jejuni

    Machado, L., Woodacre, A., Hameed, A. & Marsden, G. L., 19 May 2020, In : Frontiers in Microbiology. 11, 677, p. 1-11 11 p.

    Research output: Contribution to JournalReview Article

    Open Access
    File
  • A systematic review and meta-analysis of the effects of foam rolling on range of motion, recovery and markers of athletic performance

    Skinner, B., MOSS, RICHARD. & Hammond, L., 6 Feb 2020, In : Journal of Bodywork and Movement Therapies. 24, 3, p. 105-122 17 p.

    Research output: Contribution to JournalArticle

  • Open Access
  • Activities

    Understanding the brain in Duchenne muscular dystrophy

    Karen Anthony (Author)

    8 Jun 2020

    Activity: Academic Talks or PresentationsOral presentationResearch

    External PhD examiner

    Karen Anthony (Examiner)

    21 Jul 2020

    Activity: ExaminationsExaminationResearch

    Induction of inflammasome-dependent signalling in the human monocytic cell line THP-1 by Campylobacter lipooligosaccharides

    Alexandra Woodacre (Speaker)

    11 Apr 2019

    Activity: Academic Talks or PresentationsOral presentationResearch

    Impacts

    FDA approves first drug to treat Duchenne muscular dystrophy (DMD)

    Karen Anthony (Co-Investigator)

    Impact: Public policy impacts, Health and Well-Being impacts, Quality of life impacts, 03: Good Health and Well-Being (UN SDG)

    Student theses

    Obesity as a modulator of tumour microenvironment and anti-tumour responses in a mouse model

    Author: Oday Hessian Al-Zubaidi, R., 9 Dec 2019

    Supervisor: Stover, C. (External person) (Supervisor) & Machado, L. (Supervisor)

    Student thesis: Doctoral Thesis