Karen Anthony

Dr

  • Senior Lecturer in Molecular Bioscience, Science

Accepting PhD Students

Willing to speak to media

20072018
If you made any changes in Pure these will be visible here soon.

Research Output 2007 2018

Filter
Article
2018

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures

Hiller, M., Falzarano, M. S., Garcia-Jimenez, I., Sardone, V., Verheul, R. C., Popplewell, L., Anthony, K., Ruiz-Del-Yerro, E., Osman, H., Goeman, J. J., Mamchaoui, K., Dickson, G., Ferlini, A., Muntoni, F., Aartsma-Rus, A., Arechavala-Gomeza, V., Datson, N. A. & Spitali, P., 2 Oct 2018, In : PLoS ONE. 13, 10, p. 1-15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Duchenne Muscular Dystrophy
Antisense Oligonucleotides
Exons
Cell Culture Techniques
Polymerase Chain Reaction
2017

A UV cross-linking method combined with infrared imaging to analyse RNA–protein interactions

Malmqvist, T., Spickett, C., Gallo, J-M. & Anthony, K., 5 Jun 2017, In : Biology Methods & Protocols. 2, 1, p. 1-4 4 p., 1.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Infrared imaging
Labeling
RNA
Untranslated Regions
RNA Probes

Health and wellbeing amongst older people research in Northamptonshire

Poole, H., Sixsmith, J., Parkes, J., Ward, A., Pyer, M., Campbell, J., Machado, L., Rehling, T., Youell, J., Carter, J., Oyebode, J., O’Malley, M., Anthony, K., Rogers, S., Jones, J., Siddons, L., Smith, L-A., Kay, T., Fraser, M., Score, J. & 8 others, El Khoury, L., Hameed, A., Albalbeisi, N., Durrant, L. G., Al-Zubaidi, R., Al-Rayahi, I., da Silva, K. & Taylor, J., 1 Aug 2017, In : East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series. 15

Research output: Contribution to journalArticleResearch

Open Access
File
health
research practice
commitment
Values
2014

Biochemical characterization of patients with in-frame or out-of-frame DMD deletions pertinent to Exon 44 or 45 skipping

Anthony, K., Arechavala-Gomeza, V., Ricotti, V., Torelli, S., Feng, L., Janghra, N., Tasca, G., Guglieri, M., Barresi, R., Armaroli, A., Ferlini, A., Bushby, K., Straub, V., Ricci, E., Sewry, C., Morgan, J. & Muntoni, F., 1 Jan 2014, In : JAMA Neurology. 71, 1

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Duchenne Muscular Dystrophy
Exons
Dystrophin
Phenotype
Muscular Dystrophies

Dystrophin quantification: biological and translational research implications

Anthony, K., Arechavala-Gomeza, V., Taylor, L. E., Vulin, A., Kaminoh, Y., Torelli, S., Feng, L., Janghra, N., Bonne, G., Beuvin, M., Barresi, R., Henderson, M., Laval, S., Lourbakos, A., Campion, G., Straub, V., Voit, T., Sewry, C. A., Morgan, J. E., Flanigan, K. M. & 1 others, Muntoni, F., 25 Nov 2014, In : Neurology. 83, 22

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Dystrophin
Translational Medical Research
Immunohistochemistry
Western Blotting
Clinical Trials

Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A

Malmqvist, T., Anthony, K. & Gallo, J-M., 10 Oct 2014, In : Brain Research. 1584, p. 22-27 6 p.

Research output: Contribution to journalArticleResearchpeer-review

File
Peptide Elongation Factors
Axons
RNA
Messenger RNA
Neurons
2013

A Novel Morpholino Oligomer Targeting ISS-N1 Improves Rescue of Severe Spinal Muscular Atrophy Transgenic Mice

Zhou, H., Janghra, N., Mitrpant, C., Dickinson, R. L., Anthony, K., Price, L., Eperon, I. C., Wilton, S. D., Morgan, J. & Muntoni, F., Mar 2013, In : Human Gene Therapy. p. 331-342 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Spinal Muscular Atrophy
Morpholinos
Transgenic Mice
Antisense Oligonucleotides
Exons
2012

Antisense Oligonucleotide-Mediated Exon Skipping for Duchenne Muscular Dystrophy: Progress and Challenges

Arechavala-Gomeza, V., Anthony, K., Morgan, J. & Muntoni, F., 1 Jun 2012, In : Current Gene Therapy. p. 152-160 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Duchenne Muscular Dystrophy
Antisense Oligonucleotides
Exons
Dystrophin
Open Reading Frames

Exon Skipping Quantification by Quantitative Reverse-Transcription Polymerase Chain Reaction in Duchenne Muscular Dystrophy Patients Treated with the Antisense Oligomer Eteplirsen

Anthony, K., Feng, L., Arechavala-Gomeza, V., Guglieri, M., Straub, V., Bushby, K., Cirak, S., Morgan, J. & Muntoni, F., Oct 2012, In : Human Gene Therapy Methods. p. 336-345 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Duchenne Muscular Dystrophy
Reverse Transcription
Exons
Polymerase Chain Reaction
Dystrophin

Restoration of the dystrophin-associated glycoprotein complex after exon skipping therapy in duchenne muscular dystrophy

Cirak, S., Feng, L., Anthony, K., Arechavala-Gomeza, V., Torelli, S., Sewry, C., Morgan, J. E. & Muntoni, F., 2012, In : Molecular Therapy. p. 462-467 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Dystrophin
Duchenne Muscular Dystrophy
Exons
Glycoproteins
Nitric Oxide Synthase Type I
2011

Dystrophin quantification and clinical correlations in Becker muscular dystrophy: Implications for clinical trials

Anthony, K., Cirak, S., Torelli, S., Tasca, G., Feng, L., Arechavala-Gomeza, V., Armaroli, A., Guglieri, M., Straathof, C. S., Verschuuren, J. J., Aartsma-Rus, A., Helderman-Van Den Enden, P., Bushby, K., Straub, V., Sewry, C., Ferlini, A., Ricci, E., Morgan, J. E. & Muntoni, F., 2011, In : Brain. p. 3544-3556 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Dystrophin
Duchenne Muscular Dystrophy
Clinical Trials
Exons
Dystrophin-Associated Proteins

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: An open-label, phase 2, dose-escalation study

Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Abbs, S., Garralda, M. E., Bourke, J., Wells, D. J., Dickson, G., Wood, M. J., Wilton, S. D., Straub, V., Kole, R., Shrewsbury, S. B., Sewry, C., Morgan, J. E., Bushby, K. & Muntoni, F., 13 Aug 2011, In : The Lancet. p. 595-605 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Morpholinos
Dystrophin
Duchenne Muscular Dystrophy
Exons
Safety
2010

Aberrant RNA processing events in neurological disorders

Anthony, K. & Gallo, J. M., 18 Jun 2010, In : Brain Research. p. 67-77 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Nervous System Diseases
RNA
Alternative Splicing
RNA Stability
Amyotrophic Lateral Sclerosis
2009

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

Rodriguez-Martin, T., Anthony, K., Garcia-Blanco, M. A., Mansfield, S. G., Anderton, B. H. & Gallo, J. M., 2009, In : Human Molecular Genetics. p. 3266-3273 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Trans-Splicing
Spliceosomes
Frontotemporal Dementia
Exons
Mutation
2007

Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4

Chapple, P. J., Anthony, K., Martin, T. R., Dev, A., Cooper, T. A. & Gallo, J. M., 15 Nov 2007, In : Human Molecular Genetics. p. 2760-2769 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Trinucleotide Repeats
RNA-Binding Proteins
Exons
Brain
Alternative Splicing