Clinically significant missense variants in human GALNT3, GALNT8, GALNT12, and GALNT13 genes: Intriguing in silico findings

Medicine & Life Sciences

• Amino Acids 17%
• Breast Neoplasms 15%
• Calcinosis 60%
• Catalytic Domain 21%
• Colorectal Neoplasms 19%
• Computer Simulation 91%
• Disease Susceptibility 26%
• Genes 39%
• Glycosylation 100%
• Hyperostosis 34%
• Hyperostosis-hyperphosphatemia syndrome 53%
• Hyperphosphatemic Familial Tumoral Calcinosis 47%
• Inborn Genetic Diseases 22%
• Mutation 54%
• Neoplasms 23%
• Proteins 8%
• Transferases 99%

Chemical Compounds

• Acid 8%
• Charge Density 23%
• Chemistry 14%
• Disorder 20%
• Enzyme Activity 19%
• Glycosylation 96%
• Metabolic 19%
• Mutation 82%
• Protein 10%
• Reduction 11%
• Substitution Reaction 15%
• Transferase Reaction 39%