Epigenetics, Exercise and the immune system

Mark Antrobus, Saul Cuttell, Lee Machado*

*Corresponding author for this work

Research output: Contribution to Book/ReportChapterpeer-review

Abstract

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

Key Features
Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes
Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics
Original languageEnglish
Title of host publicationEpigenetics of Exercise and Sports: Concepts, Methods, and Current Research
Subtitle of host publicationTranslational Epigenetics
EditorsStuart Raleigh
PublisherElsevier
Chapter8
Pages183-199
ISBN (Electronic)9780128209370
ISBN (Print)9780128206829
DOIs
Publication statusPublished - 13 Jul 2021

Publication series

NameTranslational Epigenetic
PublisherElsevier
Volume25

Keywords

  • Epigenetics
  • immunity
  • Exercise

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