Evaluation of skin lesions in diabetic patients: A systematic review and meta-analysis

Amin Hosseinian Far, Nader Salari, Melika Hosseinian-Far, Hossein Kavoussi, Rostam Jalali, Aliakbar Vaisi-Raygani, Shabnam Rasoulpoor, Shna Rasoulpoor*, Masoud Mohammadi*, Shervin Shabani

*Corresponding author for this work

Research output: Contribution to JournalReview Articlepeer-review


Backgroud: Prevalence of skin lesions among diabetic patients is a major health concern. Therefore, this systematic review and meta-analysis study was conducted to determine the prevalence of skin lesions in diabetic patients. Methods: To identify and select relevant articles, the SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) databases were searched without a lower time limit and until April 2020. The random effects model was used to perform the analysis, and the heterogeneity of studies was assessed using the I2 index. Data were analyzed within the Comprehensive Meta-Analysis (Version 2) software. Results: After evaluating the 22 final articles with a total sample size of 8406, the prevalence of skin lesions among diabetes patients were found as 70.3% (95% CI: 63–76.7%). Moreover, according to the meta-regression analysis, the effect of ‘sample size’ on th prevalence of skin lesions was significantly different in diabetes patients (p <0.05). Conclusion: The results of this study show that skin lesions are common in diabetes patients. Therefore, appropriate policies needs to be adopted to improve the situation and to monitor patients and outcomes at all levels.
Original languageEnglish
Pages (from-to)1909-1916
Number of pages8
JournalJournal of Diabetes and Metabolic Disorders
Issue number2
Early online date9 Sept 2020
Publication statusPublished - 9 Sept 2020


  • Meta-analysis
  • Systematic review
  • Diabetic
  • Skin lesions
  • Diabetes
  • Prevalence


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