Prevalence of Organ‐Specific Autoantibodies in Childhood‐ and Adult‐Onset Type 1 Diabetes

Sue Allen, Devendra D, Jorg Huber

Research output: Contribution to JournalArticlepeer-review

Abstract

There are no studies that compare the prevalence of organ‐specific autoantibodies (OSAs) between adult (≥ 16 years) and childhood‐onset type 1 diabetes (T1D). We evaluated the prevalence of the following OSAs: thyroid peroxidase, thyroid receptor, parietal cell, intrinsic factor, tissue transglutaminase, adrenal cortex, mitochondrial, smooth muscle, liver kidney microsomal, and ovarian autoantibodies. Three hundred twenty‐seven (327) adults were screened for one or more of these OSAs. The prevalence of all the OSAs studied was similar in both groups. The most prevalent OSA observed was tissue transglutaminase (childhood‐onset disease = 14.3%; adult‐onset disease = 13.6%). This study did not demonstrate a distinct difference in the prevalence of OSAs between adult‐ and childhood‐onset T1D patients.
Original languageEnglish
Pages (from-to)260-262
Number of pages2
JournalImmunology of Diabetes
Volume1150
Issue number1
DOIs
Publication statusPublished - 15 Dec 2008
Externally publishedYes

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