Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib

Keyphrases

• ADP-ribose 14%
• Cell Permeable 14%
• Class-specific 14%
• Control Cell 14%
• Delayed Resolution 14%
• DNA Binding 14%
• DNA-dependent Protein Kinase (DNA-PK) 14%
• First-in-class 14%
• Genetic Findings 14%
• Induced Activation 14%
• Ionizing Radiation 57%
• Mitotic Progression 14%
• Monotherapy 14%
• Olaparib 100%
• PARP Inhibitor (PARPi) 100%
• Poly(ADP-ribose) 28%
• Poly(ADP-ribose) Glycohydrolase 100%
• Poly(ADP-ribose) Metabolism 14%
• Poly(ADP-ribose) Polymerase 42%
• PRKDC 14%
• RAD51 Foci 14%
• Radiation Effects 14%
• Radiation-induced DNA Damage 14%
• Radiation-protective Agents 14%
• Radiosensitization 100%
• Sensitizer 14%
• Tankyrase 14%
• Therapeutic Potential 14%

Medicine and Dentistry

• Adenosine Diphosphate Ribose 10%
• DNA Binding 10%
• DNA Damage 10%
• Glycosidase 100%
• Ionizing Radiation 40%
• Monotherapy 10%
• Olaparib 100%
• PARP1 100%
• Poly ADP Ribose Polymerase 30%
• Poly(adenosine Diphosphate Ribose) 100%
• Radiosensitization 100%
• Radiosensitizer 10%
• Sensitization 10%
• Tankyrase 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Diphosphate Ribose 10%
• Glycosidase 100%
• Ionizing Radiation 40%
• Monotherapy 10%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 30%
• Olaparib 100%
• Poly(adenosine Diphosphate Ribose) 100%
• Radiosensitizing Agent 10%
• Tankyrase 10%