Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Katerina Kumpan, Amit Nathubhai, Chenlu Zhang, Pauline J Wood, Matthew D Lloyd, Andrew S Thompson, Teemu Haikarainen, Lari Lehtiö, Michael D Threadgill

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Chemistry

Pharmacology, Toxicology and Pharmaceutical Science