Suction force-suction distance relation during aspiration thrombectomy for ischaemic stroke: a computational fluid dynamics study

Yubing Shi, D. Cheshire, F. Lally, C. Roffe

Research output: Contribution to journalArticle

Abstract

Acute Ischemic Stroke (AIS) is the major type of stroke occurring in patients. Aspiration thrombectomy, which uses suction to remove the thrombosis, is a promising technique in the clinical treatment of AIS patients. In this research a computational fluid dynamics (CFD) analysis was conducted to model the blood flow dynamics in a simplified cerebral model during an aspiration thrombectomy procedure. The flow system being analysed was a typical in vitro cerebral flow model, and the system parameters were set based on the clinical and in vitro data reported in open literature. The simulated flow field features showed good correlation with the in vitro response as reported in literature. The CFD study provides detailed technical data including the peak velocity occurring at the catheter tip and the suction force-suction distance relation during the aspiration thrombectomy procedure, which are useful new knowledge and have the potential to influence future catheter design as well as clinical operational protocols used during thrombectomy intervention.
Original languageEnglish
Pages (from-to)1-8
JournalPhysics in Medicine
Volume3
DOIs
Publication statusE-pub ahead of print - 12 Dec 2016

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Thrombectomy
Suction
Hydrodynamics
Stroke
Catheters
Clinical Protocols
Thrombosis
Research
In Vitro Techniques
Therapeutics

Cite this

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abstract = "Acute Ischemic Stroke (AIS) is the major type of stroke occurring in patients. Aspiration thrombectomy, which uses suction to remove the thrombosis, is a promising technique in the clinical treatment of AIS patients. In this research a computational fluid dynamics (CFD) analysis was conducted to model the blood flow dynamics in a simplified cerebral model during an aspiration thrombectomy procedure. The flow system being analysed was a typical in vitro cerebral flow model, and the system parameters were set based on the clinical and in vitro data reported in open literature. The simulated flow field features showed good correlation with the in vitro response as reported in literature. The CFD study provides detailed technical data including the peak velocity occurring at the catheter tip and the suction force-suction distance relation during the aspiration thrombectomy procedure, which are useful new knowledge and have the potential to influence future catheter design as well as clinical operational protocols used during thrombectomy intervention.",
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Suction force-suction distance relation during aspiration thrombectomy for ischaemic stroke : a computational fluid dynamics study. / Shi, Yubing; Cheshire, D.; Lally, F.; Roffe, C.

In: Physics in Medicine, Vol. 3, 12.12.2016, p. 1-8.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Suction force-suction distance relation during aspiration thrombectomy for ischaemic stroke

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AU - Shi, Yubing

AU - Cheshire, D.

AU - Lally, F.

AU - Roffe, C.

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AB - Acute Ischemic Stroke (AIS) is the major type of stroke occurring in patients. Aspiration thrombectomy, which uses suction to remove the thrombosis, is a promising technique in the clinical treatment of AIS patients. In this research a computational fluid dynamics (CFD) analysis was conducted to model the blood flow dynamics in a simplified cerebral model during an aspiration thrombectomy procedure. The flow system being analysed was a typical in vitro cerebral flow model, and the system parameters were set based on the clinical and in vitro data reported in open literature. The simulated flow field features showed good correlation with the in vitro response as reported in literature. The CFD study provides detailed technical data including the peak velocity occurring at the catheter tip and the suction force-suction distance relation during the aspiration thrombectomy procedure, which are useful new knowledge and have the potential to influence future catheter design as well as clinical operational protocols used during thrombectomy intervention.

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