The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease

Hannah Young; Ellen M. Castle; Juliet Briggs; Christy Walkin; Roseanne Billany; Elham Asgari; Sunil Bhandari; Nicolette Bishop; Kate Bramham; James Burton; Jackie Campbell; Joseph Chilcot; Nicola Cooper; Vashist Deelchand; Matthew Graham-Brown; Lynda Haggis; Alexander Hamilton; Mark Jesky; Philip Kalra; Pelagia Koufaki; Jamie Macdonald; Kieran McCafferty; Andrew Nixon; Helen Noble; Zoe Saynor; Maarten Taal; James Tollit; David Wheeler; Thomas Wilkinson; Sharlene A. Greenwood

doi:10.1038/s41598-023-50507-4

The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease

Hannah Young^*, Ellen M. Castle, Juliet Briggs, Christy Walkin, Roseanne Billany, Elham Asgari, Sunil Bhandari, Nicolette Bishop, Kate Bramham, James Burton, Jackie Campbell, Joseph Chilcot, Nicola Cooper, Vashist Deelchand, Matthew Graham-Brown, Lynda Haggis, Alexander Hamilton, Mark Jesky, Philip Kalra, Pelagia KoufakiJamie Macdonald, Kieran McCafferty, Andrew Nixon, Helen Noble, Zoe Saynor, Maarten Taal, James Tollit, David Wheeler, Thomas Wilkinson, Sharlene A. Greenwood

^*Corresponding author for this work

Health, Education & Society - Research

Research output: Contribution to Journal › Article › peer-review

Abstract

This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physical activity sessions, educational blogs and videos, and peer support. In this mixed-methods, multicentre randomised waitlist-controlled internal pilot, adults with established CKD were recruited from five NHS hospitals and randomised 1:1 to Kidney BEAM or waitlist control. Feasibility outcomes were based upon a priori progression criteria. Acceptability was primarily explored via individual semi-structured interviews (n = 15). Of 763 individuals screened, n = 519 (68%, 95% CI 65 to 71%) were eligible. Of those eligible, n = 303 (58%, 95% CI 54–63%) did not respond to an invitation to participate by the end of the pilot period. Of the 216 responders, 50 (23%, 95% CI 18–29%) consented. Of the 42 randomised, n = 22 (10 (45%) male; 49 ± 16 years; 14 (64%) White British) were allocated to Kidney BEAM and n = 20 (12 (55%) male; 56 ± 11 years; 15 (68%) White British) to the waitlist control group. Overall, n = 15 (30%, 95% CI 18–45%) withdrew during the pilot phase. Participants completed a median of 14 (IQR 5–21) sessions. At baseline, 90–100% of outcome data (patient reported outcome measures and a remotely conducted physical function test) were completed and 62–83% completed at 12 weeks follow-up. Interview data revealed that remote trial procedures were acceptable. Participants’ reported that Kidney BEAM increased their opportunity and motivation to be physically active, however, lack of time remained an ongoing barrier to engagement with the DHI. An randomised controlled trial of Kidney BEAM is feasible and acceptable, with adaptations to increase recruitment, retention and engagement.

Original language	English
Article number	700
Pages (from-to)	1-21
Number of pages	21
Journal	Scientific Reports
Volume	14
DOIs	https://doi.org/10.1038/s41598-023-50507-4
Publication status	Published - 6 Jan 2024

Bibliographical note

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Keywords

Digital health
Mixed methods
e-health
telemedicine
remote trial

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Young_etal_2024_The_development_and_internal_pilot_trial_of_a_digital_physical_activity_and_emotional_well-being_intervention_(Kidney_BEAM)_for_people_with_chronic_kidney_diseaseFinal published version, 1.38 MBLicence: CC BY

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Young, H., Castle, E. M., Briggs, J., Walkin, C., Billany, R., Asgari, E., Bhandari, S., Bishop, N., Bramham, K., Burton, J., Campbell, J., Chilcot, J., Cooper, N., Deelchand, V., Graham-Brown, M., Haggis, L., Hamilton, A., Jesky, M., Kalra, P., ... Greenwood, S. A. (2024). The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease. Scientific Reports, 14, 1-21. Article 700. https://doi.org/10.1038/s41598-023-50507-4

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abstract = "This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physical activity sessions, educational blogs and videos, and peer support. In this mixed-methods, multicentre randomised waitlist-controlled internal pilot, adults with established CKD were recruited from five NHS hospitals and randomised 1:1 to Kidney BEAM or waitlist control. Feasibility outcomes were based upon a priori progression criteria. Acceptability was primarily explored via individual semi-structured interviews (n = 15). Of 763 individuals screened, n = 519 (68%, 95% CI 65 to 71%) were eligible. Of those eligible, n = 303 (58%, 95% CI 54–63%) did not respond to an invitation to participate by the end of the pilot period. Of the 216 responders, 50 (23%, 95% CI 18–29%) consented. Of the 42 randomised, n = 22 (10 (45%) male; 49 ± 16 years; 14 (64%) White British) were allocated to Kidney BEAM and n = 20 (12 (55%) male; 56 ± 11 years; 15 (68%) White British) to the waitlist control group. Overall, n = 15 (30%, 95% CI 18–45%) withdrew during the pilot phase. Participants completed a median of 14 (IQR 5–21) sessions. At baseline, 90–100% of outcome data (patient reported outcome measures and a remotely conducted physical function test) were completed and 62–83% completed at 12 weeks follow-up. Interview data revealed that remote trial procedures were acceptable. Participants{\textquoteright} reported that Kidney BEAM increased their opportunity and motivation to be physically active, however, lack of time remained an ongoing barrier to engagement with the DHI. An randomised controlled trial of Kidney BEAM is feasible and acceptable, with adaptations to increase recruitment, retention and engagement.",

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author = "Hannah Young and Castle, {Ellen M.} and Juliet Briggs and Christy Walkin and Roseanne Billany and Elham Asgari and Sunil Bhandari and Nicolette Bishop and Kate Bramham and James Burton and Jackie Campbell and Joseph Chilcot and Nicola Cooper and Vashist Deelchand and Matthew Graham-Brown and Lynda Haggis and Alexander Hamilton and Mark Jesky and Philip Kalra and Pelagia Koufaki and Jamie Macdonald and Kieran McCafferty and Andrew Nixon and Helen Noble and Zoe Saynor and Maarten Taal and James Tollit and David Wheeler and Thomas Wilkinson and Greenwood, {Sharlene A.}",

note = "Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.",

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Young, H, Castle, EM, Briggs, J, Walkin, C, Billany, R, Asgari, E, Bhandari, S, Bishop, N, Bramham, K, Burton, J, Campbell, J, Chilcot, J, Cooper, N, Deelchand, V, Graham-Brown, M, Haggis, L, Hamilton, A, Jesky, M, Kalra, P, Koufaki, P, Macdonald, J, McCafferty, K, Nixon, A, Noble, H, Saynor, Z, Taal, M, Tollit, J, Wheeler, D, Wilkinson, T & Greenwood, SA 2024, 'The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease', Scientific Reports, vol. 14, 700, pp. 1-21. https://doi.org/10.1038/s41598-023-50507-4

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AU - Young, Hannah

AU - Castle, Ellen M.

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AU - Billany, Roseanne

AU - Asgari, Elham

AU - Bhandari, Sunil

AU - Bishop, Nicolette

AU - Bramham, Kate

AU - Burton, James

AU - Campbell, Jackie

AU - Chilcot, Joseph

AU - Cooper, Nicola

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AU - Graham-Brown, Matthew

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AU - Hamilton, Alexander

AU - Jesky, Mark

AU - Kalra, Philip

AU - Koufaki, Pelagia

AU - Macdonald, Jamie

AU - McCafferty, Kieran

AU - Nixon, Andrew

AU - Noble, Helen

AU - Saynor, Zoe

AU - Taal, Maarten

AU - Tollit, James

AU - Wheeler, David

AU - Wilkinson, Thomas

AU - Greenwood, Sharlene A.

N1 - Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PY - 2024/1/6

Y1 - 2024/1/6

N2 - This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physical activity sessions, educational blogs and videos, and peer support. In this mixed-methods, multicentre randomised waitlist-controlled internal pilot, adults with established CKD were recruited from five NHS hospitals and randomised 1:1 to Kidney BEAM or waitlist control. Feasibility outcomes were based upon a priori progression criteria. Acceptability was primarily explored via individual semi-structured interviews (n = 15). Of 763 individuals screened, n = 519 (68%, 95% CI 65 to 71%) were eligible. Of those eligible, n = 303 (58%, 95% CI 54–63%) did not respond to an invitation to participate by the end of the pilot period. Of the 216 responders, 50 (23%, 95% CI 18–29%) consented. Of the 42 randomised, n = 22 (10 (45%) male; 49 ± 16 years; 14 (64%) White British) were allocated to Kidney BEAM and n = 20 (12 (55%) male; 56 ± 11 years; 15 (68%) White British) to the waitlist control group. Overall, n = 15 (30%, 95% CI 18–45%) withdrew during the pilot phase. Participants completed a median of 14 (IQR 5–21) sessions. At baseline, 90–100% of outcome data (patient reported outcome measures and a remotely conducted physical function test) were completed and 62–83% completed at 12 weeks follow-up. Interview data revealed that remote trial procedures were acceptable. Participants’ reported that Kidney BEAM increased their opportunity and motivation to be physically active, however, lack of time remained an ongoing barrier to engagement with the DHI. An randomised controlled trial of Kidney BEAM is feasible and acceptable, with adaptations to increase recruitment, retention and engagement.

AB - This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physical activity sessions, educational blogs and videos, and peer support. In this mixed-methods, multicentre randomised waitlist-controlled internal pilot, adults with established CKD were recruited from five NHS hospitals and randomised 1:1 to Kidney BEAM or waitlist control. Feasibility outcomes were based upon a priori progression criteria. Acceptability was primarily explored via individual semi-structured interviews (n = 15). Of 763 individuals screened, n = 519 (68%, 95% CI 65 to 71%) were eligible. Of those eligible, n = 303 (58%, 95% CI 54–63%) did not respond to an invitation to participate by the end of the pilot period. Of the 216 responders, 50 (23%, 95% CI 18–29%) consented. Of the 42 randomised, n = 22 (10 (45%) male; 49 ± 16 years; 14 (64%) White British) were allocated to Kidney BEAM and n = 20 (12 (55%) male; 56 ± 11 years; 15 (68%) White British) to the waitlist control group. Overall, n = 15 (30%, 95% CI 18–45%) withdrew during the pilot phase. Participants completed a median of 14 (IQR 5–21) sessions. At baseline, 90–100% of outcome data (patient reported outcome measures and a remotely conducted physical function test) were completed and 62–83% completed at 12 weeks follow-up. Interview data revealed that remote trial procedures were acceptable. Participants’ reported that Kidney BEAM increased their opportunity and motivation to be physically active, however, lack of time remained an ongoing barrier to engagement with the DHI. An randomised controlled trial of Kidney BEAM is feasible and acceptable, with adaptations to increase recruitment, retention and engagement.

KW - Digital health

KW - Mixed methods

KW - e-health

KW - telemedicine

KW - remote trial

U2 - 10.1038/s41598-023-50507-4

DO - 10.1038/s41598-023-50507-4

M3 - Article

SN - 2045-2322

VL - 14

SP - 1

EP - 21

JO - Scientific Reports

JF - Scientific Reports

M1 - 700

ER -

The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease

Abstract

Bibliographical note

Keywords

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