Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings

M Pearl, M Zokvic, Yasina Somani, M Badrov, Sarah-Anne Hanik, Anthony Baross, Ian L Swaine, Kevin Milne, Cheri McGowan

Research output: Contribution to conference typesAbstractResearchpeer-review

Abstract

Isometric handgrip (IHG) training reduces resting blood pressure (BP) in normotensive individuals following 8-10 weeks of unilateral (4 x 2 minute sustained contractions at 30% maximal voluntary contraction (MVC) performed by the non-dominant limb, separated by 4 minutes rest) or bilateral IHG training (contractions alternating between dominant and non-dominant limb, separated by 1 minute rest), performed 3-5 times per week. Investigating the effects of a single bout of unilateral or bilateral IHG on vascular function (brachial artery flow-mediated dilation (FMD) and low-flow mediated constriction (L-FMC)) may provide insight into the underlying hypotensive mechanisms of IHG training. Eight young adult (25.3 ± 3.81 years), normotensive (99.65/61.25 ± 11.72/9.14 mmHg) women performed a single bout of bilateral (n=4) or unilateral (n=4) IHG exercise. FMD and L-FMC were assessed using ultrasound pre- and post-IHG bout. Following a single IHG bout, no significant changes were observed in FMD (unilateral: pre- = 13.56 ± 7.8%, post- =17.26 ± 21%, bilateral: pre- = 17.11 ± 1.1%, post- = 21.18 ± 8.9%) or L-FMC (unilateral: pre- = 3.36 ± 11%, post- =-2.26 ± 16%, bilateral: pre- = -2.86 ± 3.1%, post- = -1.94 ± 9.7%) in either group (all p > 0.05). Taken together these preliminary data suggest that in young healthy women, irrespective of isometric exercise on 1 or 2 limbs, the endothelium is not altered significantly. Further research with a larger sample is warranted to confirm that mechanisms other than improved vascular function play a role in IHG-training induced BP lowering.
Original languageEnglish
Pages1
Publication statusPublished - 14 Oct 2015
EventCanadian Society for Exercise Physiology - Hamalton, Canada, Hamalton, Canada
Duration: 14 Oct 201517 Mar 2019

Conference

ConferenceCanadian Society for Exercise Physiology
CountryCanada
CityHamalton
Period14/10/1517/03/19

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Constriction
Dilatation
Extremities
Exercise
Blood Pressure
Blood Vessels
Brachial Artery
Endothelium
Young Adult
Research

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Pearl, M., Zokvic, M., Somani, Y., Badrov, M., Hanik, S-A., Baross, A., ... McGowan, C. (2015). Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings. 1. Abstract from Canadian Society for Exercise Physiology, Hamalton, Canada.
Pearl, M ; Zokvic, M ; Somani, Yasina ; Badrov, M ; Hanik, Sarah-Anne ; Baross, Anthony ; Swaine, Ian L ; Milne, Kevin ; McGowan, Cheri. / Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings. Abstract from Canadian Society for Exercise Physiology, Hamalton, Canada.
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title = "Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings",
abstract = "Isometric handgrip (IHG) training reduces resting blood pressure (BP) in normotensive individuals following 8-10 weeks of unilateral (4 x 2 minute sustained contractions at 30{\%} maximal voluntary contraction (MVC) performed by the non-dominant limb, separated by 4 minutes rest) or bilateral IHG training (contractions alternating between dominant and non-dominant limb, separated by 1 minute rest), performed 3-5 times per week. Investigating the effects of a single bout of unilateral or bilateral IHG on vascular function (brachial artery flow-mediated dilation (FMD) and low-flow mediated constriction (L-FMC)) may provide insight into the underlying hypotensive mechanisms of IHG training. Eight young adult (25.3 ± 3.81 years), normotensive (99.65/61.25 ± 11.72/9.14 mmHg) women performed a single bout of bilateral (n=4) or unilateral (n=4) IHG exercise. FMD and L-FMC were assessed using ultrasound pre- and post-IHG bout. Following a single IHG bout, no significant changes were observed in FMD (unilateral: pre- = 13.56 ± 7.8{\%}, post- =17.26 ± 21{\%}, bilateral: pre- = 17.11 ± 1.1{\%}, post- = 21.18 ± 8.9{\%}) or L-FMC (unilateral: pre- = 3.36 ± 11{\%}, post- =-2.26 ± 16{\%}, bilateral: pre- = -2.86 ± 3.1{\%}, post- = -1.94 ± 9.7{\%}) in either group (all p > 0.05). Taken together these preliminary data suggest that in young healthy women, irrespective of isometric exercise on 1 or 2 limbs, the endothelium is not altered significantly. Further research with a larger sample is warranted to confirm that mechanisms other than improved vascular function play a role in IHG-training induced BP lowering.",
author = "M Pearl and M Zokvic and Yasina Somani and M Badrov and Sarah-Anne Hanik and Anthony Baross and Swaine, {Ian L} and Kevin Milne and Cheri McGowan",
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Pearl, M, Zokvic, M, Somani, Y, Badrov, M, Hanik, S-A, Baross, A, Swaine, IL, Milne, K & McGowan, C 2015, 'Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings' Canadian Society for Exercise Physiology, Hamalton, Canada, 14/10/15 - 17/03/19, pp. 1.

Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings. / Pearl, M; Zokvic, M; Somani, Yasina; Badrov, M; Hanik, Sarah-Anne; Baross, Anthony; Swaine, Ian L; Milne, Kevin; McGowan, Cheri.

2015. 1 Abstract from Canadian Society for Exercise Physiology, Hamalton, Canada.

Research output: Contribution to conference typesAbstractResearchpeer-review

TY - CONF

T1 - Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings

AU - Pearl, M

AU - Zokvic, M

AU - Somani, Yasina

AU - Badrov, M

AU - Hanik, Sarah-Anne

AU - Baross, Anthony

AU - Swaine, Ian L

AU - Milne, Kevin

AU - McGowan, Cheri

PY - 2015/10/14

Y1 - 2015/10/14

N2 - Isometric handgrip (IHG) training reduces resting blood pressure (BP) in normotensive individuals following 8-10 weeks of unilateral (4 x 2 minute sustained contractions at 30% maximal voluntary contraction (MVC) performed by the non-dominant limb, separated by 4 minutes rest) or bilateral IHG training (contractions alternating between dominant and non-dominant limb, separated by 1 minute rest), performed 3-5 times per week. Investigating the effects of a single bout of unilateral or bilateral IHG on vascular function (brachial artery flow-mediated dilation (FMD) and low-flow mediated constriction (L-FMC)) may provide insight into the underlying hypotensive mechanisms of IHG training. Eight young adult (25.3 ± 3.81 years), normotensive (99.65/61.25 ± 11.72/9.14 mmHg) women performed a single bout of bilateral (n=4) or unilateral (n=4) IHG exercise. FMD and L-FMC were assessed using ultrasound pre- and post-IHG bout. Following a single IHG bout, no significant changes were observed in FMD (unilateral: pre- = 13.56 ± 7.8%, post- =17.26 ± 21%, bilateral: pre- = 17.11 ± 1.1%, post- = 21.18 ± 8.9%) or L-FMC (unilateral: pre- = 3.36 ± 11%, post- =-2.26 ± 16%, bilateral: pre- = -2.86 ± 3.1%, post- = -1.94 ± 9.7%) in either group (all p > 0.05). Taken together these preliminary data suggest that in young healthy women, irrespective of isometric exercise on 1 or 2 limbs, the endothelium is not altered significantly. Further research with a larger sample is warranted to confirm that mechanisms other than improved vascular function play a role in IHG-training induced BP lowering.

AB - Isometric handgrip (IHG) training reduces resting blood pressure (BP) in normotensive individuals following 8-10 weeks of unilateral (4 x 2 minute sustained contractions at 30% maximal voluntary contraction (MVC) performed by the non-dominant limb, separated by 4 minutes rest) or bilateral IHG training (contractions alternating between dominant and non-dominant limb, separated by 1 minute rest), performed 3-5 times per week. Investigating the effects of a single bout of unilateral or bilateral IHG on vascular function (brachial artery flow-mediated dilation (FMD) and low-flow mediated constriction (L-FMC)) may provide insight into the underlying hypotensive mechanisms of IHG training. Eight young adult (25.3 ± 3.81 years), normotensive (99.65/61.25 ± 11.72/9.14 mmHg) women performed a single bout of bilateral (n=4) or unilateral (n=4) IHG exercise. FMD and L-FMC were assessed using ultrasound pre- and post-IHG bout. Following a single IHG bout, no significant changes were observed in FMD (unilateral: pre- = 13.56 ± 7.8%, post- =17.26 ± 21%, bilateral: pre- = 17.11 ± 1.1%, post- = 21.18 ± 8.9%) or L-FMC (unilateral: pre- = 3.36 ± 11%, post- =-2.26 ± 16%, bilateral: pre- = -2.86 ± 3.1%, post- = -1.94 ± 9.7%) in either group (all p > 0.05). Taken together these preliminary data suggest that in young healthy women, irrespective of isometric exercise on 1 or 2 limbs, the endothelium is not altered significantly. Further research with a larger sample is warranted to confirm that mechanisms other than improved vascular function play a role in IHG-training induced BP lowering.

M3 - Abstract

SP - 1

ER -

Pearl M, Zokvic M, Somani Y, Badrov M, Hanik S-A, Baross A et al. Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings. 2015. Abstract from Canadian Society for Exercise Physiology, Hamalton, Canada.