The geographies of disability have been an important and enduring part of Social and Cultural Geography since its inception. The journal has featured more than 100 research papers on different dimensions of disability, illness, impairment, ableism and (in)accessibility. In this virtual special issue, we selected ten of these papers to highlight key theoretical and empirical contributions made within the journal. These include the careful spatial theorisation of lived experiences of disabilities, and critical analyses of shifting landscapes and politics of care and support that shape the lives of many disabled people. Collectively, these papers also signpost avenues for future research such as engaging with relational and more-than-human geographies, and the development of a more global politics of disability.