Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold

Medicine & Life Sciences

• argifin 100%
• Solid-Phase Synthesis Techniques 65%
• Chitinases 58%
• Cyclic Peptides 58%
• aspartimide 47%
• Biological Products 40%
• stable plasma protein solution 37%
• Cyclization 30%
• X-Rays 15%
• Peptides 13%

Physics & Astronomy

• inhibitors 47%
• peptides 45%
• solid phases 38%
• synthesis 29%
• resins 20%
• products 13%
• cleavage 10%
• attachment 10%
• flexibility 9%
• manipulators 9%
• assembly 8%
• analogs 8%
• preparation 7%
• x rays 4%

Chemical Compounds

• Cyclic Peptide 47%
• Occurrence in Nature 33%
• Acidolysis 28%
• Pentapeptide 24%
• Flexibility 16%
• Cyclization Reaction 15%
• Cleavage 14%
• X-Ray 12%
• Peptide 11%