Global prevalence of sexual dysfunction among women with metabolic syndrome: a systematic review and meta-analysis

Nader Salari, Mona Moradi, Amin Hosseinian Far, Yassaman Khodayari, Masoud Mohammadi*

*Corresponding author for this work

Research output: Contribution to JournalReview Articlepeer-review


Sexual dysfunction is a common disorder among women, especially during menopause. Metabolic syndrome is a multifactorial disease that, according to previous studies, there is a relationship between the metabolic syndrome and sexual dysfunction among women. The aim of this systematic review and meta-analysis is to obtain the prevalence of Female Sexual Dysfunction (FSD) among women with metabolic syndrome, and to analyze available related evidence. In this systematic review and meta-analysis, the keywords of MeSH, female sexual dysfunction, FSD, metabolic syndrome were searched in PubMed, Web of Science, Scopus, Science Direct and Google Scholar. The searches were conducted without a lower time limit and until May 2022. The prevalence of FSD among women with metabolic syndrome was found to be 39.3% (95% CI: 28.3-51.5). In the subgroup analysis and in the review of 4 studies, the prevalence of sexual dysfunction in postmenopausal women with metabolic syndrome was 49.8% (95% CI: 26.1-73.6). Analyzing the results of the meta-regression test in examining the effect of the three factors of sample size, year of the study, age, and BMI of the patients on the heterogeneity of the meta-analysis, showed that with the increase of the sample size, the prevalence of sexual dysfunction among women with metabolic syndrome decreases (  
Original languageEnglish
Pages (from-to)1011-1019
Number of pages9
JournalJournal of Diabetes and Metabolic Disorders
Issue number2
Publication statusPublished - 28 Jul 2023

Bibliographical note

© The Author(s), under exclusive licence to Tehran University of Medical Sciences 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.


  • BMI
  • FSD
  • Female sexual dysfunction
  • Meta-analysis
  • Metabolic syndrome


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