COVID-19 and the long-term cardio-respiratory and metabolic health complications

Ruth Ashton*, Paul Ansdell, Emily Hume, Tom Maden-Wilkinson, Declan Ryan, Esme Tuttiett, Mark Faghy

*Corresponding author for this work

Research output: Contribution to JournalArticlepeer-review


Severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) transmission continues to impact people globally. Whilst the acute symptoms and management strategies are well documented, millions of people globally are experiencing a prolonged and debilitating symptom profile that is reported to last months and even years. COVID-19 is a multi-system disease however the magnitude of the effects and its associated legacy is presently not well understood. Early reports indicate that multidisciplinary approaches between clinical and non-clinical entities are needed to provide effective and rehabilitative patient support pathways and restore pre-COVID-19 quality of life and functional status. Accordingly, this review provides a summary of the impact on cardiovascular, inflammatory, respiratory, and musculoskeletal function following an acute COVID-19 infection along with the prolonged effects of long-COVID.
Original languageEnglish
Article number53
Number of pages8
JournalReviews in Cardiovascular Medicine
Issue number2
Early online date9 Feb 2022
Publication statusPublished - 9 Feb 2022


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