Projects per year
Organisation profile
Organisation profile
The Centre focuses on multidisciplinary aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression to target national and global challenges to health.
The Research Centre aims to:
- Bring together researchers examining physiological, psychological and biomechanical aspects of physical activity interventions in sedentary, active and clinical populations, and the microbiological, genetic and molecular aspects of disease progression.
- Develop research capacity by providing training for undergraduate to postdoctoral researchers and supporting early career researchers to become independent research leaders targeting national and global challenges to health.
The Centre for Physical Activity and Life Sciences is a multidisciplinary Centre including expertise in Biosciences, Sport & Exercise Sciences, Podiatry, and Occupational Therapy. The Centre includes three main Special Interest Groups; Molecular Biosciences, Sport & Exercise Medicine, and Interdisciplinary Physical Activity & Health Promotion. The main interests of researchers in these Groups are outlined below:
- Molecular Biosciences
- Immunogenetics
- Clinical genetics and genomics
- RNA-based gene therapy
- Cancer biology
- Neuromuscular and neurodegenerative disorders
- Monozygotic twin studies
- Bioethics
- Antimicrobial resistance
- Molecular Mechanisms of Bacterial Pathogenesis
- Infection control
- Sport & Exercise Medicine
- Functional decline during ageing and fall risk
- Sarcopenia and osteoporosis
- Eccentric exercise in healthy and ageing populations
- Cognitive impairment, pain and balance in ageing
- Tendinopathy
- Muscle stretching techniques and strain injury
- Isometric resistance training and hypertension
- Exercise-induced muscle damage
- Heat- and cryo-based therapy
- Concussion in impact sports Infection control
- Interdisciplinary Physical Activity & Health Promotion
- Social exercise prescription in the built environment
- Dancing groups to promote older adult health
- Sociology of physical activity
- Whole-systems partnership development
- Child physical activity and nutrition programmes
Keywords
- RC1200 Sports Medicine
Fingerprint
Profiles
-
Dr Mark Antrobus
- University of Northampton, Science - Senior Lecturer in Sport & Exercise Physiology
- Centre for Physical Activity and Life Sciences
Person: Academic
-
Dr Sindy Banga
- University of Northampton, Science - Senior Lecturer in Health Psychology
- Centre for Physical Activity and Life Sciences
Person: Academic
-
Dr Anthony Baross
- University of Northampton, Science - Senior Lecturer in Sport Studies
- Centre for Physical Activity and Life Sciences
Person: Academic
-
Brett Baxter
- University of Northampton, Science - Lecturer in Sport & Exercise Science (Kinesiology)
- Centre for Physical Activity and Life Sciences
- University of Northampton, Graduate School
Person: Ph.D.
-
Investigate the value of plasma galectin-3 and RANKL measurements in predicting disease progression and skeletal complications in Multiple Myeloma
Farahani, M., Machado, L., SIVAKUMARAN, M. & Yu, L.
2/10/23 → 2/10/24
Project: Research › Charitable Funding
-
A qualitative exploration of green space users and implications for health and well-being
Hardwicke, J., Ryan, D. & Hill, K.
Project: Internal Fund › Small Grants Scheme for Early Career Researchers
-
Evaluation of RNA trans-splicing as a therapeutic strategy for spinocerebellar ataxia, type 1
17/10/22 → 17/10/23
Project: Research › Charitable Funding
-
Investigating a role for dystrophin protein Dp71 in cell migration
27/06/22 → 8/08/22
Project: Research › Charitable Funding
File -
Promoting physical activity participation within green and blue spaces in a COVID-19 era.
1/12/20 → 31/03/21
Project: Internal Fund › QR Strategic Priorities Fund 2020/21
-
A bioinformatic analysis of the Duchenne muscular dystrophy gene and associated gene variants across human cancers
Machado, L., 7 Mar 2023, 142 p.Research output: Types of Thesis › Master's Thesis
-
A systematic literature review and meta-analysis of the effectiveness of vitamin D supplementation for patients with Duchenne muscular dystrophy
Guo, J. & Anthony, K., 15 Oct 2023, (E-pub ahead of print) In: Neuromuscular Disorders. 10 p.Research output: Contribution to Journal › Article › peer-review
Open AccessFile -
Delapré Walk Project: Are signposted walking routes an effective intervention to increase engagement in urban parks? –Natural experimental study
Ryan, D., Hardwicke, J. & Hill, K., 3 Jun 2023, In: Health and Place. 83, 103049.Research output: Contribution to Journal › Article › peer-review
-
Developing directional walking route signage for your local community: a toolbox guide.
Ryan, D., Hardwicke, J., Hill, K., Browne, J. & Clinton, R., 10 May 2023Research output: Book/Report › Technical Report
Open AccessFile -
Drafting behind LGB: Transgender athletes in the sport of cycling
Hardwicke, J., Roberts, C., Anderson, E. & Magrath, R., 11 May 2023, (Accepted/In press) In: International Review for the Sociology of Sport.Research output: Contribution to Journal › Article › peer-review
Open AccessFile
Datasets
-
Using automated active infrared counters to estimate footfall on urban park footpaths: reliability and validity testing - Supporting Dataset
Ryan, D. (Creator) & Benton, J. (Creator), University of Northampton, 1 Feb 2023
DOI: 10.24339/3ef61812-75c7-4431-8423-7358d0c296f2
Dataset
File -
Dataset for - 'Duchenne muscular dystrophy gene expression is an independent prognostic marker for low-grade glioma'
Anthony, K. (Creator) & Machado, L. (Creator), University of Northampton, Jul 2021
DOI: 10.24339/ae20690c-1bdf-48b0-8c5d-c88fbc40ad4a
Dataset
File -
Online survey responses from Parents and Providers of the Holiday Activities and Food Programme Summer 2021 evaluation
Ryan, D. (Creator), Northampton, U. (Data Collector), Bayes, N. (Creator), Bradley, S. (Contributor), Jones, P. (Creator) & Kay, T. (Contributor), University of Northampton, 2023
DOI: 10.24339/16fc3b12-9df4-4785-a429-1411960ea69e
Dataset
-
An investigation into attitudes towards, and experiences of, sexual minorities in cycling
Hardwicke, J. (Creator), University of Northampton, 15 Oct 2022
DOI: 10.24339/5011a1d2-7adb-4584-9373-de911f4d91cb
Dataset
File -
Delapre Cycling and Walking Social Prescription Feasibility Study - Community Survey Data
Hardwicke, J. (Creator) & Ryan, D. (Creator), University of Northampton, 20 Jul 2022
DOI: 10.24339/cdf4db22-fc07-4a9a-8946-5ccbffb87702
Dataset
File
Activities
-
Pan-cancer vaccines: breaking tolerance by targeting stress-induced post-translational modifications in tumours
Lee Machado (Examiner)
29 Jun 2023Activity: Examinations › Examination › Research
-
Investigating the role of DMD in head and neck cancer
Lee Machado (Author)
25 Jan 2023Activity: Academic Talks or Presentations › Invited talk › Research
File -
Effects of assisted Nordic hamstring exercise on strength, range of motion, muscle soreness and perceived exertion: a pilot study
Luke Callis (Author), Brett Baxter (Author) & Tony Kay (Author)
7 Jul 2023Activity: Academic Talks or Presentations › Conference Presentation
-
Training and contralateral effects of 6 weeks isokinetic eccentric exercise on plantarflexor muscle-tendon mechanics
Tony Kay (Author), Jessica Tysoe (Author), Anthony J Blazevich (Author) & Brett Baxter (Author)
7 Jul 2023Activity: Academic Talks or Presentations › Conference Presentation
-
Technology, Pedagogy and Education (Journal)
Emma Whewell (Reviewer)
1 Mar 2023 → …Activity: Publication Peer-review and Editorial Work › Editorial work › Research
Impacts
-
FDA approves first drug to treat Duchenne muscular dystrophy (DMD)
Karen Anthony (Co-Investigator)
Impact: Public policy impacts, Health and Well-Being impacts, Quality of life impacts, 03: Good Health and Well-Being (UN SDG)
-
Identification of the microorganisms responsible for acute head and neck infections
Alexandra Woodacre (Principal Investigator), Jazmine Cox (Co-Investigator), Jodie Score (Co-Investigator) & Philip Ameerally (Facilitator)
Impact: 03: Good Health and Well-Being (UN SDG)
Student theses
-
Admission patterns of paediatric patients aged 0-4 years diagnosed with respiratory conditions between Emergency Department (ED) and acute paediatrics and its relationship to zero-day admissions.
Author: Wright, V., Jul 2020Supervisor: Harris, N. (Supervisor) & Beeson, P. (Supervisor)
Student thesis: Doctoral Thesis
File -
Characterising the Role of the Calcium-dependent Citrullinating Enzyme Peptidyl Arginine Deiminase 2 in Ovarian Cancer
Author: Albalbeisi, N., Oct 2019Supervisor: Livingstone, I. (Supervisor), Machado, L. (Supervisor) & Anthony, K. (Supervisor)
Student thesis: Doctoral Thesis
File -
Exploring domestic rabbit (Oryctolagus cuniculus) personality utilising behaviour coding, behaviour testing and a novel behaviour rating tool
Author: Ellis, C. F., Sept 2020Supervisor: Holt, C. (Supervisor) & McCormick, W. (Supervisor)
Student thesis: Doctoral Thesis
File -
Validating a Proposed Data Mining Approach (SLDM) for Motion Wearable Sensors to Detect the Early Signs of Lameness in Sheep
Author: Al-Rubaye, Z., Jul 2020Supervisor: Turner, S. (Supervisor), Al-Sherbaz, A. (Supervisor) & McCormick, W. (Supervisor)
Student thesis: Doctoral Thesis
File -
Welfare issues in Italian heavy pig production
Author: Di Martino, G., Feb 2020Supervisor: Livingstone, I. (Supervisor), McCormick, W. (Supervisor) & Machado, L. (Supervisor)
Student thesis: Doctoral Thesis
File
Press/Media
-
Campaigners call for popular Northampton footpath to reopen
2/10/23
1 item of Media coverage
Press/Media
-
-
UON spawns new social enterprise to improve quality of life into old age
Alexander Lehner & Neill Friedman
8/10/22 → 13/10/22
2 items of Media coverage
Press/Media
-
Cyclists need more awareness about protective headgear
Jack Hardwicke
17/06/22
1 Media contribution
Press/Media
-
Only one in five competitive cyclists aware that helmets do not protect from concussion, according to new research
Jack Hardwicke & Brett Baxter
16/06/22
1 item of Media coverage
Press/Media