Photo of Alexandra Woodacre

Alexandra Woodacre

Dr

  • Senior Lecturer in Molecular Bioscience, Science

Accepting PhD Students

20082013
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Personal profile

Biography

Alex began her career studying Microbiology at the University of Leeds, including a year’s work experience placement at the Public Health Laboratory Service in Preston, and graduated in 2003. She took a PhD position at the University of Leicester to study transcriptional regulation in the pathogenic fungus Candida albicans, and after her PhD was awarded she remained at Leicester in a variety of postdoctoral research positions including working on phase variation in the infectious bacteria Campylobacter jejuni and Streptococcus pneumoniae. Alex joined the University of Northampton as a Lecturer in 2017.

Research Interests

Alex’s research focuses on how infectious bacteria respond to changes in their environment and how this affects their ability to grow and cause disease in humans. She is interested in the very different responses of Campylobacter jejuni during colonisation of the chicken gut and of Streptococcus pneumoniae in the human lungs and bloodstream. These organisms are leading causes of gastroenteritis and pneumonia respectively, contributing to extremely high levels of disease and mortality worldwide.

Supervision

Amber Hameed; Sports, Exercise and Life Science

Characterisation of the lipooligosaccharide (LOS) biosynthesis gene clusters  in Campylobacter species.

 

Lewis Waterfield; Sports, Exercise and Life Science

Response of Streptococcus pneumoniae to metal and oxidative stresses.

Teaching Interests

Alex contributes to teaching on the following programmes, focusing on Microbiology, Epidemiology, Genetics and Molecular biology

  • BSc Human Bioscience
  • BSc Biomedical Science
  • BSc Biology
  • BSc Health Studies
  • MSc Molecular Biosciences

Alex is module leader for the following modules:

  • SLS2010 Health and Disease
  • SLS2014 Techniques in Molecular Biology
  • SLS3011 Pathogen Biology
  • MSc Molecular Bioscience Dissertation Modules

Education/Academic qualification

Bachelor, University of Leeds

PhD, University of Leicester

External positions

Junior Editor, Access Microbiology, Microbiology Society

1 Oct 2018 → …

Honorary Visiting Fellow, University of Leicester

1 Jul 20171 Jul 2022

Fingerprint Dive into the research topics where Alexandra Woodacre is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Candida albicans Medicine & Life Sciences
Copper Medicine & Life Sciences
Campylobacter jejuni Medicine & Life Sciences
Yeasts Medicine & Life Sciences
Iron Medicine & Life Sciences
Streptococcus pneumoniae Medicine & Life Sciences
Hyphae Medicine & Life Sciences
Ceramides Medicine & Life Sciences

Research Output 2008 2013

A novel Sit4 phosphatase complex is involved in the response to ceramide stress in yeast

Woodacre, A., Lone, M. A., Jablonowski, D., Schneiter, R., Giorgini, F. & Schaffrath, R., 2013, In : Oxidative Medicine and Cellular Longevity. 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Ceramides
Phosphoric Monoester Hydrolases
Yeasts
Sphingolipids
phytosphingosine

Ferric reductase genes involved in high-affinity iron uptake are differentially regulated in yeast and hyphae of Candida albicans

Jeeves, R. E., Mason, R. P., Woodacre, A. & Cashmore, A. M., 21 Jun 2011, In : Yeast. 28, 9, p. 629-644 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Hyphae
Candida albicans
Iron
Yeasts
Genes

Copper-dependent transcriptional regulation by Candida albicans Mac1p

Woodacre, A., Mason, R. P., Jeeves, R. E. & Cashmore, A. M., 2008, In : Microbiology. p. 1502-1512 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Candida albicans
Copper
Saccharomyces cerevisiae
Genes
Response Elements

Activities 2018 2019

  • 3 Participating in a conference or workshop
  • 1 Editorial work
  • 1 Publication Peer-review
  • 1 Oral presentation

Access Microbiology (Journal)

Alexandra Woodacre (Reviewer)
25 Mar 2019

Activity: Publication Peer-review and Editorial WorkPublication Peer-reviewResearch

Induction of inflammasome-dependent signalling in the human monocytic cell line THP-1 by Campylobacter lipooligosaccharides

Alexandra Woodacre (Speaker)
11 Apr 2019

Activity: Academic Talks or PresentationsOral presentationResearch

American Society for Microbiology

Lee Machado (Participant), Alexandra Woodacre (Participant), Gemma L Marsden (Participant), Amber Hameed (Participant)
20 Jun 201924 Jun 2019

Activity: Participating in or organising a conference or workshopParticipating in a conference or workshopResearch

File

5th Midlands Molecular Microbiology Meeting

Alexandra Woodacre (Participant), Amber Hameed (Participant)
13 Sep 201814 Sep 2018

Activity: Participating in or organising a conference or workshopParticipating in a conference or workshopResearch

Microbiology Society Annual Conference

Alexandra Woodacre (Participant)
11 Apr 2018

Activity: Participating in or organising a conference or workshopParticipating in a conference or workshopTeaching

Press / Media