The coding polymorphism (rs1130866) within the surfactant protein B gene is known to associate with certain respiratory abnormalities. We investigated, using spirometry and fluorescence-based PCR, whether this variant influenced pulmonary function in healthy, nonsmoking men. We found no association of pulmonary function with genotype at the rs1130866 locus.
- pulmonary function
Raleigh, S. M., Davies, B. M., Cleal, D., & Ribbans, W. J. (2007). No association between coding polymorphism within Exon 4 of the human surfactant protein B gene and pulmonary function in healthy men. Journal of Physiological Sciences, 57(3). https://doi.org/10.2170/physiolsci.SC002607