No association between coding polymorphism within Exon 4 of the human surfactant protein B gene and pulmonary function in healthy men

Stuart M Raleigh; Benjamin M Davies; David Cleal; William J Ribbans

doi:10.2170/physiolsci.SC002607

No association between coding polymorphism within Exon 4 of the human surfactant protein B gene and pulmonary function in healthy men

Stuart M Raleigh, Benjamin M Davies, David Cleal, William J Ribbans

Research output: Contribution to Journal › Article › peer-review

Abstract

The coding polymorphism (rs1130866) within the surfactant protein B gene is known to associate with certain respiratory abnormalities. We investigated, using spirometry and fluorescence-based PCR, whether this variant influenced pulmonary function in healthy, nonsmoking men. We found no association of pulmonary function with genotype at the rs1130866 locus.

Original language	English
Journal	Journal of Physiological Sciences
Volume	57
Issue number	3
DOIs	https://doi.org/10.2170/physiolsci.SC002607
Publication status	Published - 1 Jun 2007

Keywords

genotype
pulmonary function

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2170/physiolsci.SC002607

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title = "No association between coding polymorphism within Exon 4 of the human surfactant protein B gene and pulmonary function in healthy men",

abstract = "The coding polymorphism (rs1130866) within the surfactant protein B gene is known to associate with certain respiratory abnormalities. We investigated, using spirometry and fluorescence-based PCR, whether this variant influenced pulmonary function in healthy, nonsmoking men. We found no association of pulmonary function with genotype at the rs1130866 locus.",

keywords = "genotype, pulmonary function",

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AU - Raleigh, Stuart M

AU - Davies, Benjamin M

AU - Cleal, David

AU - Ribbans, William J

PY - 2007/6/1

Y1 - 2007/6/1

N2 - The coding polymorphism (rs1130866) within the surfactant protein B gene is known to associate with certain respiratory abnormalities. We investigated, using spirometry and fluorescence-based PCR, whether this variant influenced pulmonary function in healthy, nonsmoking men. We found no association of pulmonary function with genotype at the rs1130866 locus.

AB - The coding polymorphism (rs1130866) within the surfactant protein B gene is known to associate with certain respiratory abnormalities. We investigated, using spirometry and fluorescence-based PCR, whether this variant influenced pulmonary function in healthy, nonsmoking men. We found no association of pulmonary function with genotype at the rs1130866 locus.

KW - genotype

KW - pulmonary function

U2 - 10.2170/physiolsci.SC002607

DO - 10.2170/physiolsci.SC002607

M3 - Article

SN - 1880-6562

VL - 57

JO - Journal of Physiological Sciences

JF - Journal of Physiological Sciences

IS - 3

ER -

No association between coding polymorphism within Exon 4 of the human surfactant protein B gene and pulmonary function in healthy men

Abstract

Keywords

UN SDGs

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