Accepting PhD Students

PhD projects

PhD and MPhil projects are available. Current research interests include: -Neuropathophysiology of Duchenne muscular dystrophy -RNA processing of the dystrophin gene -Therapeutic targeting of dystrophin in the brain -Role of the DMD gene in cancer -RNA processing in neurodegeneration -RNA-based gene therapy/therapeutics Please get in touch by e-mail or telephone.

Willing to speak to media

20072020

Research output per year

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Research Output

2020

The Duchenne muscular dystrophy gene and cancer

Jones, L., Naidoo, M., Machado, L. & Anthony, K., 22 Oct 2020, (Accepted/In press) In : Cellular oncology (Dordrecht).

Research output: Contribution to JournalReview Article

2019

Dystrophin Dp71 and the Neuropathophysiology of Duchenne Muscular Dystrophy

Naidoo, M. & Anthony, K., 13 Dec 2019, In : Molecular Neurobiology. p. 1-20 21 p.

Research output: Contribution to JournalArticle

Open Access
2018

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures

Hiller, M., Falzarano, M. S., Garcia-Jimenez, I., Sardone, V., Verheul, R. C., Popplewell, L., Anthony, K., Ruiz-Del-Yerro, E., Osman, H., Goeman, J. J., Mamchaoui, K., Dickson, G., Ferlini, A., Muntoni, F., Aartsma-Rus, A., Arechavala-Gomeza, V., Datson, N. A. & Spitali, P., 2 Oct 2018, In : PLoS ONE. 13, 10, p. 1-15 15 p.

Research output: Contribution to JournalArticle

Open Access
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Open Access
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2017

A UV cross-linking method combined with infrared imaging to analyse RNA–protein interactions

Malmqvist, T., Spickett, C., Gallo, J-M. & Anthony, K., 5 Jun 2017, In : Biology Methods & Protocols. 2, 1, p. 1-4 4 p., 1.

Research output: Contribution to JournalArticle

Open Access
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Open Access
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Health and wellbeing amongst older people research in Northamptonshire

Poole, H., Sixsmith, J., Parkes, J., Ward, A., Pyer, M., Campbell, J., Machado, L., Rehling, T., Youell, J., Carter, J., Oyebode, J., O’Malley, M., Anthony, K., Rogers, S., Jones, J., Siddons, L., Smith, L-A., Kay, A. D., Fraser, M., Score, J. & 8 others, El Khoury, L., Hameed, A., Albalbeisi, N., Durrant, L. G., Al-Zubaidi, R., Al-Rayahi, I., da Silva, K. & Taylor, J., 1 Aug 2017, (East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series).

Research output: Working PaperDiscussion Paper

Open Access
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2015

G.P.147 - Outcome measures for Duchenne muscular dystrophy from ambulant to non-ambulant: implications for clinical trials

Ricotti, V., Eagle, M., Butler, J., Decostre, V., Deborah, R., Moraux, A., Anthony, K., Sleby, V., Guglieri, M., Van der Holst, M., Jansen, M., Morgan, J., de Groot, I., Niks, E., Verschuuren, J., Servais, L., Hogrel, J. Y., Voit, T., Straub, V. & Muntoni, F., 1 Oct 2015, In : Neuromuscular Disorders. 25, Supp 2

Research output: Contribution to JournalAbstract

Open Access
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G.P.228 - Micro RNA profile associated with the dystrophin level in Becker muscular dystrophy

Zaharieva, I., Cirak, S., Anthony, K., Feng, L., Tasca, G., Ferlini, A., Morgan, J. & Muntoni, F., 1 Oct 2015, In : Neuromuscular Disorders. 25, Supp 2

Research output: Contribution to JournalAbstract

Open Access
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2014

Biochemical characterization of patients with in-frame or out-of-frame DMD deletions pertinent to Exon 44 or 45 skipping

Anthony, K., Arechavala-Gomeza, V., Ricotti, V., Torelli, S., Feng, L., Janghra, N., Tasca, G., Guglieri, M., Barresi, R., Armaroli, A., Ferlini, A., Bushby, K., Straub, V., Ricci, E., Sewry, C., Morgan, J. & Muntoni, F., 1 Jan 2014, In : JAMA Neurology. 71, 1, p. 32-40 9 p.

Research output: Contribution to JournalArticle

Open Access
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Dystrophin quantification: biological and translational research implications

Anthony, K., Arechavala-Gomeza, V., Taylor, L. E., Vulin, A., Kaminoh, Y., Torelli, S., Feng, L., Janghra, N., Bonne, G., Beuvin, M., Barresi, R., Henderson, M., Laval, S., Lourbakos, A., Campion, G., Straub, V., Voit, T., Sewry, C. A., Morgan, J. E., Flanigan, K. M. & 1 others, Muntoni, F., 25 Nov 2014, In : Neurology. 83, 22, p. 2062-2069 8 p.

Research output: Contribution to JournalArticle

Open Access
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Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A

Malmqvist, T., Anthony, K. & Gallo, J-M., 10 Oct 2014, In : Brain Research. 1584, p. 22-27 6 p.

Research output: Contribution to JournalArticle

File
2013

A Novel Morpholino Oligomer Targeting ISS-N1 Improves Rescue of Severe Spinal Muscular Atrophy Transgenic Mice

Zhou, H., Janghra, N., Mitrpant, C., Dickinson, R. L., Anthony, K., Price, L., Eperon, I. C., Wilton, S. D., Morgan, J. & Muntoni, F., Mar 2013, In : Human Gene Therapy. p. 331-342 12 p.

Research output: Contribution to JournalArticle

Assessing T cell-mediated immune response to dystrophin in the natural history of Duchenne muscular dystrophy

Anthony, K., Ricotti, V., Guglieri, M., Servais, L., Voit, T., Bushby, K., Straub, V., Morgan, J. & Muntoni, F., 2013, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

2012

A morpholino antisense oligonucleotide rescues type I and type III SMA mice

Zhou, H., Janghra, N., Anthony, K., Morgan, J. & Muntoni, F., 2012, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

Antisense Oligonucleotide-Mediated Exon Skipping for Duchenne Muscular Dystrophy: Progress and Challenges

Arechavala-Gomeza, V., Anthony, K., Morgan, J. & Muntoni, F., 1 Jun 2012, In : Current Gene Therapy. p. 152-160 9 p.

Research output: Contribution to JournalArticle

Biochemical and clinical variability of Becker muscular dystrophy: Predicting optimal target exons for exon skipping therapy in Duchenne muscular

Anthony, K., Arechavala-Gomeza, V., Ricotti, V., Torelli, S., Feng, L., Tasca, G., Guglieri, M., Barresi, R., Armaroli, A., Ferlini, A., Bushby, K., Straub, V., Ricci, E., Sewry, C., Morgan, J. & Muntoni, F., 2012, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

Correlation of internally deleted dystrophin and dystrophin-associated protein expression with clinical severity in Becker muscular dystrophy

Anthony, K., Cirak, S., Torelli, S., Tasca, G., Feng, L., Arechavala-Gomeza, V., Armaroli, A., Guglieri, M., Straathof, C. S., Verschuuren, J. J., Aartsma-Rus, A., Helderman-Van Den Enden, P., Bushby, K., Straub, V., Sewry, C., Ferlini, A., Ricci, E., Morgan, J. & Muntoni, F., 2012, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

Exon Skipping Quantification by Quantitative Reverse-Transcription Polymerase Chain Reaction in Duchenne Muscular Dystrophy Patients Treated with the Antisense Oligomer Eteplirsen

Anthony, K., Feng, L., Arechavala-Gomeza, V., Guglieri, M., Straub, V., Bushby, K., Cirak, S., Morgan, J. & Muntoni, F., Oct 2012, In : Human Gene Therapy Methods. p. 336-345 10 p.

Research output: Contribution to JournalArticle

Exon-skipping therapy for Duchenne muscular dystrophy - Authors' reply

Arechavala-Gomeza, V., Cirak, S., Anthony, K., Morgan, J. & Muntoni, F., 14 Jan 2012, In : The Lancet.

Research output: Contribution to JournalLetter

Restoration of the dystrophin-associated glycoprotein complex after exon skipping therapy in duchenne muscular dystrophy

Cirak, S., Feng, L., Anthony, K., Arechavala-Gomeza, V., Torelli, S., Sewry, C., Morgan, J. E. & Muntoni, F., 2012, In : Molecular Therapy. p. 462-467 6 p.

Research output: Contribution to JournalArticle

2011

A TaqMan qRT-PCR assay to assess patient response in exon skipping clinical trials for Duchenne muscular dystrophy

Anthony, K., Feng, L., Arechavala-Gomeza, V., Morgan, J. & Muntoni, F., 2011.

Research output: Contribution to ConferencePaper

Dystrophin quantification and clinical correlations in Becker muscular dystrophy: Implications for clinical trials

Anthony, K., Cirak, S., Torelli, S., Tasca, G., Feng, L., Arechavala-Gomeza, V., Armaroli, A., Guglieri, M., Straathof, C. S., Verschuuren, J. J., Aartsma-Rus, A., Helderman-Van Den Enden, P., Bushby, K., Straub, V., Sewry, C., Ferlini, A., Ricci, E., Morgan, J. E. & Muntoni, F., 2011, In : Brain. p. 3544-3556 13 p.

Research output: Contribution to JournalArticle

Exon skipping and dystrophin restoration in Duchenne muscular dystrophy patients after systemic phosphorodiamidate morpholino oligomer treatment

Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Garralda, M. E., Wells, D. J., Dickson, G., Wood, M. J., Wilton, S. D., Straub, V., Shrewsbury, S. B., Sewry, C., Morgan, J., Bushby, K. & Muntoni, F., 2011, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: An open-label, phase 2, dose-escalation study

Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Abbs, S., Garralda, M. E., Bourke, J., Wells, D. J., Dickson, G., Wood, M. J., Wilton, S. D., Straub, V., Kole, R., Shrewsbury, S. B., Sewry, C., Morgan, J. E., Bushby, K. & Muntoni, F., 13 Aug 2011, In : The Lancet. p. 595-605 11 p.

Research output: Contribution to JournalArticle

P07 The feasibility of exon skipping to restore the reading frame in DMD patients with duplications

kim, J., Anthony, K., cloke, V., yau, M., Abbs, S., Morgan, J. & Muntoni, F., 2011, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

Quantification of exon skipping in Duchenne muscular dystrophy by qRT-PCR

Anthony, K., Morgan, J. & Muntoni, F., 2011, In : Neuromuscular Disorders.

Research output: Contribution to JournalAbstract

2010

Aberrant RNA processing events in neurological disorders

Anthony, K. & Gallo, J. M., 18 Jun 2010, In : Brain Research. p. 67-77 11 p.

Research output: Contribution to JournalArticle

2009

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

Rodriguez-Martin, T., Anthony, K., Garcia-Blanco, M. A., Mansfield, S. G., Anderton, B. H. & Gallo, J. M., 2009, In : Human Molecular Genetics. p. 3266-3273 8 p.

Research output: Contribution to JournalArticle

2007

Characterization of the Neuronal RNA-binding Protein CELF3, a Modulator of Tau Exon 10 Alternative Splicing

Chapple, P. J., Rodriguez-Martin, T., Anthony, K., Cooper, T. A. & Gallo, J-M., 2007.

Research output: Contribution to ConferencePaper

Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4

Chapple, P. J., Anthony, K., Martin, T. R., Dev, A., Cooper, T. A. & Gallo, J. M., 15 Nov 2007, In : Human Molecular Genetics. p. 2760-2769 10 p.

Research output: Contribution to JournalArticle

Identification of regulators of tau mRNA localisation

Anthony, K., Chapple, P. J. & Gallo, J-M., 2007.

Research output: Contribution to ConferencePaper